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2,5-Deoxyfructosazine (hydrochloride)

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Catalog No. T37276Cas No. 17460-13-8

2,5-Deoxyfructosazine is a pyrazine derivative found in cured tobacco and used as a flavoring agent in the food and tobacco industry. It can be produced via pyrolytic decomposition of natural compounds or through the reaction of sugars with alcoholic ammonia. Additionally, it forms from the breakdown of D-glucosamine at neutral pH. Similar to glucosamine, 2,5-deoxyfructosazine exhibits DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM).

2,5-Deoxyfructosazine (hydrochloride)

2,5-Deoxyfructosazine (hydrochloride)

😃Good
Catalog No. T37276Cas No. 17460-13-8
2,5-Deoxyfructosazine is a pyrazine derivative found in cured tobacco and used as a flavoring agent in the food and tobacco industry. It can be produced via pyrolytic decomposition of natural compounds or through the reaction of sugars with alcoholic ammonia. Additionally, it forms from the breakdown of D-glucosamine at neutral pH. Similar to glucosamine, 2,5-deoxyfructosazine exhibits DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM).
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1 mg$129 35 days
5 mg$248 35 days
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Product Introduction

Bioactivity
Description
2,5-Deoxyfructosazine is a pyrazine derivative found in cured tobacco and used as a flavoring agent in the food and tobacco industry. It can be produced via pyrolytic decomposition of natural compounds or through the reaction of sugars with alcoholic ammonia. Additionally, it forms from the breakdown of D-glucosamine at neutral pH. Similar to glucosamine, 2,5-deoxyfructosazine exhibits DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50 = ~1.25 mM).
Chemical Properties
Molecular Weight304.3
FormulaC12H20N2O7
Cas No.17460-13-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 3 mg/mL (9.86 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (32.86 mM), Sonication is recommended.
Solution Preparation Table
DMSO/PBS (pH 7.2)
1mg5mg10mg50mg
1 mM3.2862 mL16.4312 mL32.8623 mL164.3115 mL
5 mM0.6572 mL3.2862 mL6.5725 mL32.8623 mL
PBS (pH 7.2)
1mg5mg10mg50mg
10 mM0.3286 mL1.6431 mL3.2862 mL16.4312 mL
20 mM0.1643 mL0.8216 mL1.6431 mL8.2156 mL

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Keywords

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