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2-(Isopentylamino)naphthalene-1,4-dione

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Catalog No. T37950Cas No. 1607447-79-9

2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).

2-(Isopentylamino)naphthalene-1,4-dione

2-(Isopentylamino)naphthalene-1,4-dione

😃Good
Catalog No. T37950Cas No. 1607447-79-9
2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).
Pack SizePriceAvailabilityQuantity
1 mg$11035 days
5 mg$39435 days
10 mg$69535 days
25 mg$1,46035 days
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Product Introduction

Bioactivity
Description
2-(Isopentylamino)naphthalene-1,4-dione is a vitamin K analog.1It inhibits spasms induced by pentylenetetrazole and tonic hindlimb extension induced by maximal electroshock (MES) in mice (ED50s = 349.2 and 108.1 mg/kg, respectively). It also protects mice against seizures in the 6 Hz psychomotor seizure test (ED50s = 152.7 and 263.7 mg/kg at stimulus intensities of 32 and 44 mA, respectively).
1.Li, X., Himes, R.A., Prosser, L.C., et al.Discovery of the first vitamin K analogue as a potential treatment of pharmacoresistant seizuresJ. Med. Chem.63(11)5865-5878(2020)
Chemical Properties
Molecular Weight243.306
FormulaC15H17NO2
Cas No.1607447-79-9
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL
DMF: 30 mg/mL
DMSO:PBS (pH 7.2) (1:2): 0.33 mg/mL
Ethanol: 20 mg/mL

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Keywords

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