Shopping Cart

Remove All
Your shopping cart is currently empty

2N12B

Name: 2N12B
Brand: TargetMol
SKU: T203745
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T203745

Alias 2N12-B, 2N-12B, 2-N12B

2N12B is an ionizable cationic lipid containing a disulfide bond (pKa = 6.5), utilized in the creation of lipid nanoparticles (LNPs) for the delivery of siRNA both in vitro and in vivo.

2N12B

😃Good

Catalog No. T203745Alias 2N12-B, 2N-12B, 2-N12B

2N12B is an ionizable cationic lipid containing a disulfide bond (pKa = 6.5), utilized in the creation of lipid nanoparticles (LNPs) for the delivery of siRNA both in vitro and in vivo.

Pack Size	Price	Availability	Quantity
10 mg	Inquiry	Backorder
50 mg	Inquiry	Backorder

Bulk & Custom

Add to Cart

Questions

Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	2N12B is an ionizable cationic lipid containing a disulfide bond (pKa = 6.5), utilized in the creation of lipid nanoparticles (LNPs) for the delivery of siRNA both in vitro and in vivo.
Alias	2N12-B, 2N-12B, 2-N12B

Chemical Properties

Molecular Weight	903.5
Formula	C₄₂H₈₂N₂O₆S₆

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc