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3',4'-Dihydroxyflavonol
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Catalog No. T14036Cas No. 6068-78-6
Alias DiOHF
3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant that reduces superoxide levels and improves nitric oxide (NO) function in the mesenteric arteries of diabetic rats[1].
3',4'-Dihydroxyflavonol
😃Good
Catalog No. T14036Alias DiOHFCas No. 6068-78-6
3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant that reduces superoxide levels and improves nitric oxide (NO) function in the mesenteric arteries of diabetic rats[1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $77 | 5 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 3',4'-Dihydroxyflavonol (DiOHF) is an effective antioxidant that reduces superoxide levels and improves nitric oxide (NO) function in the mesenteric arteries of diabetic rats[1]. |
| In vitro | 3',4'-Dihydroxyflavonol (DiOHF) preserves nitric oxide (NO) activity in the presence of elevated reactive oxygen species (ROS) and reduces vascular contraction through Ca2+ desensitization in permeabilized third-order branches of rat mesenteric arteries[2]. DiOHF improves NO activity in diabetes by reducing Nox2-dependent superoxide production and preventing eNOS uncoupling, thereby enhancing endothelial function[1]. |
| Alias | DiOHF |
| Molecular Weight | 270.24 |
| Formula | C15H10O5 |
| Cas No. | 6068-78-6 |
| Relative Density. | 1.31g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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