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3'-Deoxyuridine-5'-triphosphate trisodium

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Catalog No. T35658

'3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II by competitively blocking UTP incorporation into RNA with a dissociation constant (Ki) of 2.0 μM[1].

3'-Deoxyuridine-5'-triphosphate trisodium
Other Forms of 3'-Deoxyuridine-5'-triphosphate trisodium:
3'-Deoxyuridine-5'-triphosphateT3565769199-40-2
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3'-Deoxyuridine-5'-triphosphate trisodium

😃Good
Catalog No. T35658
'3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II by competitively blocking UTP incorporation into RNA with a dissociation constant (Ki) of 2.0 μM[1].
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Product Introduction

Bioactivity
Description
'3'-Deoxyuridine-5'-triphosphate trisodium (3'-dUTP trisodium) is a nucleotide analogue that inhibits DNA-dependent RNA polymerases I and II by competitively blocking UTP incorporation into RNA with a dissociation constant (Ki) of 2.0 μM[1].
In vitro
3'-Deoxyuridine-5'-triphosphate (3'-dUTP), synthesized from cordycepin in good yield, strongly inhibits UTP incorporation into RNA by RNA polymerases competitively. It is useful for molecular studies on RNA synthesis with chromatin, isolated nuclei, or permeable cells, as it does not affect poly (rA) synthesis[1].
Chemical Properties
Molecular Weight534.08
FormulaC9H12N2Na3O14P3
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

3'-Deoxyuridine-5'-triphosphate trisodium3'Deoxyuridine5'triphosphate trisodium3' Deoxyuridine 5' triphosphate trisodium3'-Deoxyuridine-5'-triphosphate
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