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3,4-Dibromo-Mal-PEG2-N-Boc

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Catalog No. T14025Cas No. 1807537-43-4

3,4-Dibromo-Mal-PEG2-N-Boc is a PEGylated PROTAC linker used in PROTAC synthesis [1].

3,4-Dibromo-Mal-PEG2-N-Boc

3,4-Dibromo-Mal-PEG2-N-Boc

😃Good
Catalog No. T14025Cas No. 1807537-43-4
3,4-Dibromo-Mal-PEG2-N-Boc is a PEGylated PROTAC linker used in PROTAC synthesis [1].
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5 mg$335 days
10 mg$465 days
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Product Introduction

Bioactivity
Description
3,4-Dibromo-Mal-PEG2-N-Boc is a PEGylated PROTAC linker used in PROTAC synthesis [1].
In vitro
PROTACs are compounds that consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade the target proteins[1].
Chemical Properties
Molecular Weight486.15
FormulaC15H22Br2N2O6
Cas No.1807537-43-4
Relative Density.1.609 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

PEGsAlkyl/ether3,4-Dibromo-Mal-PEG2-N-Boc3,4-Dibromo-Mal-PEG-2-N-Boc3,4DibromoMalPEG2NBoc3,4 Dibromo Mal PEG2 N Boc
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