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3-Oxotirucalla-7,24-dien-21-oic acid

Catalog No. TN2979Cas No. 82464-35-5

3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines.

3-Oxotirucalla-7,24-dien-21-oic acid

3-Oxotirucalla-7,24-dien-21-oic acid

Catalog No. TN2979Cas No. 82464-35-5
3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines.
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5 mg$769Backorder
1 mL x 10 mM (in DMSO)$928Backorder
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Product Introduction

Bioactivity
Description
3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines.
Targets&IC50
MCF-7 cells:27.5 μM, HIV-1:20 microg/mL
In vitro
3-Oxotirucalla-7,24-dien-21-oic acid was isolated from the dichloromethane extract of the stem of Luvunga scandens (Roxb.) Buch-Ham ex Wight & Arn, Rutaceae. The cytotoxic potential of the 3-Oxotirucalla-7,24-dien-21-oic acid was determined by MTT assay against the human breast adenocarcinoma cell line (MCF-7). 3-Oxotirucalla-7,24-dien-21-oic acid showed potent cytotoxicity against the MCF-7 cell line with IC50 values of 27.5 μM, respectively. This result suggested their potential activity as antitumor agents.[1]
Chemical Properties
Molecular Weight454.68
FormulaC30H46O3
Cas No.82464-35-5
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Keywords

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