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3-Oxotirucalla-7,24-dien-21-oic acid
3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines.
Catalog No. TN2979Cas No. 82464-35-5
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3-Oxotirucalla-7,24-dien-21-oic acid
Catalog No. TN2979Cas No. 82464-35-5
3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $769 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $928 | Backorder |
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Bioactivity
Chemical Properties
| Description | 3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines. |
| Targets&IC50 | HIV-1:20 microg/mL, MCF-7 cells:27.5 μM |
| In vitro | 3-Oxotirucalla-7,24-dien-21-oic acid was isolated from the dichloromethane extract of the stem of Luvunga scandens (Roxb.) Buch-Ham ex Wight & Arn, Rutaceae. The cytotoxic potential of the 3-Oxotirucalla-7,24-dien-21-oic acid was determined by MTT assay against the human breast adenocarcinoma cell line (MCF-7). 3-Oxotirucalla-7,24-dien-21-oic acid showed potent cytotoxicity against the MCF-7 cell line with IC50 values of 27.5 μM, respectively. This result suggested their potential activity as antitumor agents.[1] |
| Molecular Weight | 454.68 |
| Formula | C30H46O3 |
| Cas No. | 82464-35-5 |
Storage & Solubility Information
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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