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3-Epidehydrotumulosic acid exhibits inhibitory effects on AAPH-induced haemolysis of erythrocytes.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $2,068 | Backorder | |
1 mL x 10 mM (in DMSO) | $2,530 | Backorder |
Description | 3-Epidehydrotumulosic acid exhibits inhibitory effects on AAPH-induced haemolysis of erythrocytes. |
In vitro | These two, and eight other known compounds isolated from the sclerotium, poricoic acid B (3), poricoic acid A (4), tumulosic acid (5), dehydrotumulosic acid (6), 3-Epidehydrotumulosic acid (7), polyporenic acid C (8), 25-hydroxy-3-Epidehydrotumulosic acid (9), and dehydroabietic acid methyl ester (10), showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Evaluation of the cytotoxicity of compounds 1 and 4 against human cancer cell lines revealed that 1 was significantly cytotoxic to leukemia HL-60 cells [GI(50) (concentration that yields 50% growth) value 39.3 nM], although it showed only moderate cytotoxicity to the other cells. Compound 4 exhibited moderate cytotoxicity to all of the cancer cell lines tested[1] |
Molecular Weight | 484.71 |
Formula | C31H48O4 |
Cas No. | 167775-54-4 |
Relative Density. | 1.11 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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