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3-Epidehydrotumulosic acid

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Catalog No. TN1007Cas No. 167775-54-4

3-Epidehydrotumulosic acid exhibits inhibitory effects on AAPH-induced haemolysis of erythrocytes.

3-Epidehydrotumulosic acid

3-Epidehydrotumulosic acid

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Catalog No. TN1007Cas No. 167775-54-4
3-Epidehydrotumulosic acid exhibits inhibitory effects on AAPH-induced haemolysis of erythrocytes.
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5 mg$2,068Backorder
1 mL x 10 mM (in DMSO)$2,530Backorder
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Product Introduction

Bioactivity
Description
3-Epidehydrotumulosic acid exhibits inhibitory effects on AAPH-induced haemolysis of erythrocytes.
In vitro
These two, and eight other known compounds isolated from the sclerotium, poricoic acid B (3), poricoic acid A (4), tumulosic acid (5), dehydrotumulosic acid (6), 3-Epidehydrotumulosic acid (7), polyporenic acid C (8), 25-hydroxy-3-Epidehydrotumulosic acid (9), and dehydroabietic acid methyl ester (10), showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Evaluation of the cytotoxicity of compounds 1 and 4 against human cancer cell lines revealed that 1 was significantly cytotoxic to leukemia HL-60 cells [GI(50) (concentration that yields 50% growth) value 39.3 nM], although it showed only moderate cytotoxicity to the other cells. Compound 4 exhibited moderate cytotoxicity to all of the cancer cell lines tested[1]
Chemical Properties
Molecular Weight484.71
FormulaC31H48O4
Cas No.167775-54-4
Relative Density.1.11 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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