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3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $769 | Backorder | |
1 mL x 10 mM (in DMSO) | $928 | Backorder |
Description | 3-Oxotirucalla-7,24-dien-21-oic acid, the first known compound isolated from Polygonum spp., can also be obtained from the roots of Black Cohosh. This compound demonstrated potent cytotoxicity against MCF-7 cell lines. |
Targets&IC50 | MCF-7 cells:27.5 μM, HIV-1:20 microg/mL |
In vitro | 3-Oxotirucalla-7,24-dien-21-oic acid was isolated from the dichloromethane extract of the stem of Luvunga scandens (Roxb.) Buch-Ham ex Wight & Arn, Rutaceae. The cytotoxic potential of the 3-Oxotirucalla-7,24-dien-21-oic acid was determined by MTT assay against the human breast adenocarcinoma cell line (MCF-7). 3-Oxotirucalla-7,24-dien-21-oic acid showed potent cytotoxicity against the MCF-7 cell line with IC50 values of 27.5 μM, respectively. This result suggested their potential activity as antitumor agents.[1] |
Molecular Weight | 454.68 |
Formula | C30H46O3 |
Cas No. | 82464-35-5 |
Smiles | C[C@@]12C=3[C@@]([C@]4(C)[C@@](CC3)(C(C)(C)C(=O)CC4)[H])(CC[C@@]1(C)[C@]([C@H](CCC=C(C)C)C(O)=O)(CC2)[H])[H] |
Relative Density. | no data available |
Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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