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4-(N-Boc-amino)piperidine

Name: 4-(N-Boc-amino)piperidine
Brand: TargetMol
SKU: T38292
Rating: 4.5 (1 reviews)

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Catalog No. T38292Cas No. 73874-95-0

4-(N-Boc-amino)piperidine is an organic building block.1,2It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents.

4-(N-Boc-amino)piperidine

😃Good

Catalog No. T38292Cas No. 73874-95-0

4-(N-Boc-amino)piperidine is an organic building block.1,2It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents.

Pack Size	Price	Availability	Quantity
1 g	Inquiry	35 days
5 g	Inquiry	35 days

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Product Introduction

Bioactivity

Description

4-(N-Boc-amino)piperidine is an organic building block.1,2It has been used in the synthesis of aminopiperidine antiviral chemokine (C-C motif) receptor 5 (CCR5) antagonists and antibacterial agents.
1.Burrows, J.N., Cumming, J.G., Fillery, S.M., et al.Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureasBioorg. Med. Chem. Lett.15(1)25-28(2005) 2.Reck, F., Alm, R., Brassil, P., et al.Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II: Broad-spectrum antibacterial agents with reduced hERG activityJ. Med. Chem.54(22)7834-7847(2011)

Chemical Properties

Molecular Weight	200.282
Formula	C₁₀H₂₀N₂O₂
Cas No.	73874-95-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Chloroform: 30 mg/mL (149.79 mM), Sonication is recommended.

Solution Preparation Table

Chloroform

	1mg	5mg	10mg	50mg
1 mM	4.9930 mL	24.9648 mL	49.9296 mL	249.6480 mL
5 mM	0.9986 mL	4.9930 mL	9.9859 mL	49.9296 mL
10 mM	0.4993 mL	2.4965 mL	4.9930 mL	24.9648 mL
20 mM	0.2496 mL	1.2482 mL	2.4965 mL	12.4824 mL
50 mM	0.0999 mL	0.4993 mL	0.9986 mL	4.9930 mL
100 mM	0.0499 mL	0.2496 mL	0.4993 mL	2.4965 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

4(NBocamino)piperidine4-(N-Boc-amino)piperidine4 (N Boc amino)piperidine