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4-Nitrophenyl Phenylphosphonate

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Catalog No. T37895Cas No. 57072-35-2

4-Nitrophenyl phenylphosphonate is a substrate for 5'-nucleotide phosphodiesterases. It is a more preferable substrate to 5'-nucleotide phosphodiesterases than naturally occurring nucleotides or bis(4-nitrophenyl) phosphate because of its stability, ease of synthesis, and higher rate of hydrolysis under saturating conditions.

4-Nitrophenyl Phenylphosphonate

4-Nitrophenyl Phenylphosphonate

😃Good
Catalog No. T37895Cas No. 57072-35-2
4-Nitrophenyl phenylphosphonate is a substrate for 5'-nucleotide phosphodiesterases. It is a more preferable substrate to 5'-nucleotide phosphodiesterases than naturally occurring nucleotides or bis(4-nitrophenyl) phosphate because of its stability, ease of synthesis, and higher rate of hydrolysis under saturating conditions.
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500 mgInquiry35 days
1 gInquiry35 days
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Product Introduction

Bioactivity
Description
4-Nitrophenyl phenylphosphonate is a substrate for 5'-nucleotide phosphodiesterases. It is a more preferable substrate to 5'-nucleotide phosphodiesterases than naturally occurring nucleotides or bis(4-nitrophenyl) phosphate because of its stability, ease of synthesis, and higher rate of hydrolysis under saturating conditions.
Chemical Properties
Molecular Weight279.19
FormulaC12H10NO5P
Cas No.57072-35-2
Relative Density.1.45 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 14 mg/mL (50.15 mM), Sonication is recommended.
DMF: 30 mg/mL (107.45 mM), Sonication is recommended.
DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL (1.79 mM), Sonication is recommended.
Solution Preparation Table
DMF:PBS(pH 7.2)(1:1)/DMSO/DMF
1mg5mg10mg50mg
1 mM3.5818 mL17.9090 mL35.8179 mL179.0895 mL
DMSO/DMF
1mg5mg10mg50mg
5 mM0.7164 mL3.5818 mL7.1636 mL35.8179 mL
10 mM0.3582 mL1.7909 mL3.5818 mL17.9090 mL
20 mM0.1791 mL0.8954 mL1.7909 mL8.9545 mL
50 mM0.0716 mL0.3582 mL0.7164 mL3.5818 mL
DMF
1mg5mg10mg50mg
100 mM0.0358 mL0.1791 mL0.3582 mL1.7909 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Keywords

4-Nitrophenyl Phenylphosphonate4Nitrophenyl Phenylphosphonate4 Nitrophenyl Phenylphosphonate
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