Powder: -20°C for 3 years | In solvent: -80°C for 1 year
4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 μg | 35 days | $ 123.00 | |
50 μg | 35 days | $ 230.00 | |
100 μg | 35 days | $ 430.00 | |
250 μg | 35 days | $ 950.00 |
Description | 4-oxo Docosahexaenoic acid (4-oxo DHA) is a putative metabolite of DHA with antiproliferative and PPARγ agonist activity. It inhibits the growth of several triple negative breast cancer cell lines (MCF-10F, trMCF, bsMCF, MDA-MB-231, and BT549) at 50-100 μM, however it increased proliferation of MCF-7 cells. 4-oxo DHA binds covalently to PPARγ and activates gene transcription in luciferase reporter assays and in dendritic cells with EC50 values of approximately 8-16 μM. |
Molecular Weight | 342.479 |
Formula | C22H30O3 |
CAS No. | 845673-74-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PBS (pH 7.2): 0.1 mg/mL
DMF: 50 mg/mL
DMSO: 50 mg/mL
Ethanol: 50 mg/mL
You can also refer to dose conversion for different animals. More
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4-oxo Docosahexaenoic Acid 845673-74-7 4 oxo Docosahexaenoic Acid 4oxo Docosahexaenoic Acid inhibitor inhibit