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42-(2-Tetrazolyl)rapamycin

Catalog No. T10158Cas No. 221877-56-1

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog.

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Pack Size	Price	Availability	Quantity
50 mg	$997	Backorder

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Product Introduction

Bioactivity

Description

42-(2-Tetrazolyl)rapamycin is a prodrug compound of a rapamycin analog.

Chemical Properties

Molecular Weight	966.21
Formula	C52H79N5O12
Cas No.	221877-56-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 130 mg/mL (134.55 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0350 mL	5.1749 mL	10.3497 mL	51.7486 mL
5 mM	0.2070 mL	1.0350 mL	2.0699 mL	10.3497 mL
10 mM	0.1035 mL	0.5175 mL	1.0350 mL	5.1749 mL
20 mM	0.0517 mL	0.2587 mL	0.5175 mL	2.5874 mL
50 mM	0.0207 mL	0.1035 mL	0.2070 mL	1.0350 mL
100 mM	0.0103 mL	0.0517 mL	0.1035 mL	0.5175 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc