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Cholesterol-5α,6α-epoxide

Name: Cholesterol-5α,6α-epoxide
Brand: TargetMol
SKU: T35973
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T35973Cas No. 1250-95-9

Alias NSC 18176, Epoxycholesterol, 5α,6α-epoxy Cholestanol

Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE application.

Cholesterol-5α,6α-epoxide

🥰Excellent

Purity: 99.15%

Catalog No. T35973Alias NSC 18176, Epoxycholesterol, 5α,6α-epoxy CholestanolCas No. 1250-95-9

Pack Size	Price	Availability
25 mg	$31	In Stock
50 mg	$52	In Stock
100 mg	$75	In Stock

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Purity:99.15%

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COA HPLC HNMR

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Cholesterol-5α,6α-epoxide (Epoxycholesterol) is the metabolite of cholesterol produced by oxidation. Cholesterol-5α,6α-epoxide induces triacylglycerol biosynthesis by binding to LXRβ following tamoxifen and PBPE application.
Alias	NSC 18176, Epoxycholesterol, 5α,6α-epoxy Cholestanol

Chemical Properties

Molecular Weight	402.65
Formula	C₂₇H₄₆O₂
Cas No.	1250-95-9
Smiles	CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C[C@@H]4O[C@@]44C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

Storage & Solubility Information

Storage	store at low temperature \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	Ethanol: ≤ 20 mg/mL, Sonication is recommended. DMF: 2 mg/mL (4.97 mM), Sonication is recommended. DMSO: 0.1 mg/mL (0.25 mM), Sonication is recommended.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

NSC-18176NSC18176Cholesterol-5α,6α-epoxideCholesterol-5alpha,6alpha-epoxideCholesterol-5a,6a-epoxide5alpha,6alpha-epoxy Cholestanol5a,6a-epoxy Cholestanol