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5'-O-DMT-PAC-dA

Name: 5'-O-DMT-PAC-dA
Brand: TargetMol
SKU: T37139
Price: 43 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T37139Cas No. 110522-82-2

5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].

5'-O-DMT-PAC-dA

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Catalog No. T37139Cas No. 110522-82-2

5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].

Pack Size	Price	Availability	Quantity
100 mg	$42	Backorder
1 mL x 10 mM (in DMSO)	$46	Backorder

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Product Introduction

Bioactivity

Description

5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].
[1]. Schulhof JC, et, al. The final deprotection step in oligonucleotide synthesis is reduced to a mild and rapid ammonia treatment by using labile base-protecting groups. Nucleic Acids Res. 1987 Jan 26;15(2):397-416.

Chemical Properties

Molecular Weight	687.74
Formula	C₃₉H₃₇N₅O₇
Cas No.	110522-82-2

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 250 mg/mL (363.51 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.4540 mL	7.2702 mL	14.5404 mL	72.7019 mL
5 mM	0.2908 mL	1.4540 mL	2.9081 mL	14.5404 mL
10 mM	0.1454 mL	0.7270 mL	1.4540 mL	7.2702 mL
20 mM	0.0727 mL	0.3635 mL	0.7270 mL	3.6351 mL
50 mM	0.0291 mL	0.1454 mL	0.2908 mL	1.4540 mL
100 mM	0.0145 mL	0.0727 mL	0.1454 mL	0.7270 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

5'ODMTPACdA5' O DMT PAC dA5'-O-DMT-PAC-dA