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5-A-RU-PABC-Val-Cit-Fmoc

Name: 5-A-RU-PABC-Val-Cit-Fmoc
Brand: TargetMol
SKU: T40303
Price: 299 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T40303Cas No. 2677841-58-4

5-A-RU-PABC-Val-Cit-Fmoc is a precursor of 5-A-RU, a small molecule activator associated with mucosal-associated invariant T (MAIT) cells and a precursor in bacterial riboflavin synthesis.

5-A-RU-PABC-Val-Cit-Fmoc

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Purity: 98.7%

Catalog No. T40303Cas No. 2677841-58-4

5-A-RU-PABC-Val-Cit-Fmoc is a precursor of 5-A-RU, a small molecule activator associated with mucosal-associated invariant T (MAIT) cells and a precursor in bacterial riboflavin synthesis.

Pack Size	Price	Availability	Quantity
1 mg	$299	In Stock

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Purity:98.7%

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COA LCMS

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	5-A-RU-PABC-Val-Cit-Fmoc is a precursor of 5-A-RU, a small molecule activator associated with mucosal-associated invariant T (MAIT) cells and a precursor in bacterial riboflavin synthesis.
In vitro	Analysis of both in vitro and in vivo prodrugs showed that compared to 5-A-RU, 5-A-RU-PABC-Val-Cit-Fmoc induces higher levels of mucosa-associated invariant T (MAIT) cell activation.[1].

Chemical Properties

Molecular Weight	903.93
Formula	C₄₃H₅₃N₉O₁₃
Cas No.	2677841-58-4
Smiles	CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Nc2c(NC[C@H](O)[C@H](O)[C@H](O)CO)[nH]c(=O)[nH]c2=O)cc1
Relative Density.	1.47 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 80 mg/mL (132.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.1063 mL	5.5314 mL	11.0628 mL	55.3140 mL
5 mM	0.2213 mL	1.1063 mL	2.2126 mL	11.0628 mL
10 mM	0.1106 mL	0.5531 mL	1.1063 mL	5.5314 mL
20 mM	0.0553 mL	0.2766 mL	0.5531 mL	2.7657 mL
50 mM	0.0221 mL	0.1106 mL	0.2213 mL	1.1063 mL
100 mM	0.0111 mL	0.0553 mL	0.1106 mL	0.5531 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

5-A-RU-PABC-Val-Cit-Fmoc5 A RU PABC Val Cit Fmoc5ARUPABCValCitFmoc