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5-hydroxy Propranolol

Name: 5-hydroxy Propranolol
Brand: TargetMol
SKU: T36237
Rating: 4.5 (1 reviews)

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Catalog No. T36237Cas No. 81907-82-6

5-hydroxy Propranolol is a metabolite of propranolol , a β-adrenergic receptor antagonist. Propranolol is primarily metabolized in the liver, with cytochrome P450 isoform 2D6 directing ring hydroxylation and the generation of 5-hydroxy propranolol and related metabolites.

5-hydroxy Propranolol

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Catalog No. T36237Cas No. 81907-82-6

Pack Size	Price	Availability
500 μg	$337	35 days
1 mg	$529	35 days
5 mg	$2,470	35 days
10 mg	$4,290	35 days

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	275.348
Formula	C₁₆H₂₁NO₃
Cas No.	81907-82-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Ethanol: 30 mg/mL (108.95 mM), Sonication is recommended.

DMSO: 30 mg/mL (108.95 mM), Sonication is recommended.

DMF:PBS(pH 7.2)(1:1): 0.5 mg/mL (1.82 mM), Sonication is recommended.

DMF: 50 mg/mL (181.59 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO/DMF

	1mg	5mg	10mg	50mg
5 mM	0.7264 mL	3.6318 mL	7.2635 mL	36.3177 mL
10 mM	0.3632 mL	1.8159 mL	3.6318 mL	18.1588 mL
20 mM	0.1816 mL	0.9079 mL	1.8159 mL	9.0794 mL
50 mM	0.0726 mL	0.3632 mL	0.7264 mL	3.6318 mL
100 mM	0.0363 mL	0.1816 mL	0.3632 mL	1.8159 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

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