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Mal-β-CD

Catalog No. T19159Cas No. 104723-60-6
Alias 6-O-alpha-D-Maltosyl-beta-cyclodextrin

Mal-β-CD, a cellular cholesterol modifier, forms a soluble inclusion complex with cholesterol.

Mal-β-CD

Mal-β-CD

Catalog No. T19159Alias 6-O-alpha-D-Maltosyl-beta-cyclodextrinCas No. 104723-60-6
Mal-β-CD, a cellular cholesterol modifier, forms a soluble inclusion complex with cholesterol.
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500 mg$427-10 days
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Product Introduction

Bioactivity
Description
Mal-β-CD, a cellular cholesterol modifier, forms a soluble inclusion complex with cholesterol.
In vitro
Mal-β-CD effectively extracts cholesterol from cells by forming inclusion complexes. This reduction in cellular cholesterol triggered by Mal-β-CD is restored through the introduction of a cholesterol/Mal-β-CD inclusion complex, which replenishes the cholesterol levels without inducing cytotoxicity.
Alias6-O-alpha-D-Maltosyl-beta-cyclodextrin
Chemical Properties
Molecular Weight1459.27
FormulaC54H90O45
Cas No.104723-60-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 60.5 mg/mL (41.46 mM)
DMSO: 100 mg/mL (68.53 mM)
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM0.6853 mL3.4264 mL6.8527 mL34.2637 mL
5 mM0.1371 mL0.6853 mL1.3705 mL6.8527 mL
10 mM0.0685 mL0.3426 mL0.6853 mL3.4264 mL
20 mM0.0343 mL0.1713 mL0.3426 mL1.7132 mL
DMSO
1mg5mg10mg50mg
50 mM0.0137 mL0.0685 mL0.1371 mL0.6853 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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