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8-Br-GTP, an analog of GTP, functions as both a competitive inhibitor of FtsZ polymerization and GTPase activity (with a K i value of 31.8 μM). Moreover, it is capable of facilitating nucleic acid modification.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $970 | Backorder |
Description | 8-Br-GTP, an analog of GTP, functions as both a competitive inhibitor of FtsZ polymerization and GTPase activity (with a K i value of 31.8 μM). Moreover, it is capable of facilitating nucleic acid modification. |
In vitro | 8-Br-GTP selectively inhibits FtsZ polymerization without impacting tubulin polymerization. It exhibits two stable base orientations towards the sugar, namely anti and syn, with a marked preference for the syn conformation, constituting approximately 90% of its population [1][2]. |
Alias | 8-Bromoguanosine-5'-triphosphate, 8-Br-GTP |
Molecular Weight | 602.076 |
Formula | C10H15BrN5O14P3 |
Cas No. | 23197-98-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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