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8-Bromo-ATP
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Catalog No. T39891Cas No. 23567-97-7
Alias 8-Bromo-ATP, 8-Bromoadenosine 5'-triphosphate, 8-Br-ATP
8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and ATP analogue that exhibits cytotoxicity towards multiple myeloma cells, with an IC50 of 23.1 μM.
8-Bromo-ATP
😃Good
Catalog No. T39891Alias 8-Bromo-ATP, 8-Bromoadenosine 5'-triphosphate, 8-Br-ATPCas No. 23567-97-7
8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and ATP analogue that exhibits cytotoxicity towards multiple myeloma cells, with an IC50 of 23.1 μM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $970 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate) is a purinergic P2X receptor agonist and ATP analogue that exhibits cytotoxicity towards multiple myeloma cells, with an IC50 of 23.1 μM. |
| In vitro | Treatment with 8-Bromo-ATP (10-50 μM; 5 days) demonstrates cytotoxic effects on multiple myeloma cells (MM 1.s) as evidenced by decreased cell viability. This compound facilitates fluorescence measurements by selectively quenching specific tryptophan residues in ATPase, thereby enabling more precise analysis. Moreover, 8-Bromo-ATP significantly amplifies the dephosphorylation rate of native ATPase by 2-3 times, in the absence of divalent cations, underscoring its potential utility in biochemical research and therapeutic applications targeting ATPase-related functions. |
| Alias | 8-Bromo-ATP, 8-Bromoadenosine 5'-triphosphate, 8-Br-ATP |
| Molecular Weight | 586.077 |
| Formula | C10H15BrN5O13P3 |
| Cas No. | 23567-97-7 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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