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8-Nitroguanine

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Catalog No. T36697Cas No. 168701-80-2

8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma.

8-Nitroguanine

8-Nitroguanine

😃Good
Catalog No. T36697Cas No. 168701-80-2
8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma.
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1 mg$296 35 days
5 mg$1,200 35 days
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Product Introduction

Bioactivity
Description
8-Nitroguanine is a product of DNA nitration damage caused by reactive nitrogen species and may be a potential biomarker for the progression of malignant fibrous histiocytoma.
Chemical Properties
Molecular Weight196.12
FormulaC5H4N6O3
Cas No.168701-80-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
1 M NaOH: 50 mg/mL (254.95 mM), Sonication is recommended.
Solution Preparation Table
1 M NaOH
1mg5mg10mg50mg
1 mM5.0989 mL25.4946 mL50.9892 mL254.9460 mL
5 mM1.0198 mL5.0989 mL10.1978 mL50.9892 mL
10 mM0.5099 mL2.5495 mL5.0989 mL25.4946 mL
20 mM0.2549 mL1.2747 mL2.5495 mL12.7473 mL
50 mM0.1020 mL0.5099 mL1.0198 mL5.0989 mL
100 mM0.0510 mL0.2549 mL0.5099 mL2.5495 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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