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Amphotericin X1

Amphotericin X1
Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 μg/mL and 2 μg/mL).
Catalog No. T10311Cas No. 136135-57-4

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Amphotericin X1

Catalog No. T10311Cas No. 136135-57-4

Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2 μg/mL and 2 μg/mL).
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Product Introduction

Bioactivity
Description
Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2
Targets&IC50
A.fumigatus:2 μg/mL , Cryptococcus neoformans 451: 1 μg/mL , C. albicans 33/079:(MIC)1 μg/mL , Aspergillus niger 57A: 2 μg/mL , C.parapsilosis 937A: 8 μg/mL
In vitro
Amphotericin X1 (compound 4) exhibits antifungal activity with significantly reduced hemolytic activity (EH50: 42 μg/mL) against mammalian erythrocytes in vitro.
Chemical Properties
Molecular Weight938.118
FormulaC48H75NO17
Cas No.136135-57-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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