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Aplaviroc hydrochloride

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Catalog No. T26642Cas No. 461023-63-2
Alias GW873140A, GW-873140, GW873140, Aplaviroc HCl, AK-602, AK602, AK 602

Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.

Aplaviroc hydrochloride
Other Forms of Aplaviroc hydrochloride:
AplavirocT14307461443-59-4
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Aplaviroc hydrochloride

😃Good
Catalog No. T26642Alias GW873140A, GW-873140, GW873140, Aplaviroc HCl, AK-602, AK602, AK 602Cas No. 461023-63-2
Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc selectively inhibits the binding of a particular monoclonal antibody, 45531, to CCR5.
Pack SizePriceAvailabilityQuantity
25 mg1.083 €10-14 weeks
50 mg1.415 €10-14 weeks
100 mg2.242 €10-14 weeks
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Product Introduction

Bioactivity
Description
Aplaviroc is a human cellular CC chemokine receptor 5 (CCR5) entry inhibitor. Aplaviroc binds specifically to CCR5 and demonstrates potent anti-human immunodeficiency virus activity in vitro in the subnanomolar range. In vitro studies show that aplaviroc
Targets&IC50
HIV-1 (MOKW):0.2 nM (IC50), HIV-1 (JRFL):0.1 nM (IC50), HIV-1 (Ba-L):0.4 nM (IC50)
AliasGW873140A, GW-873140, GW873140, Aplaviroc HCl, AK-602, AK602, AK 602
Chemical Properties
Molecular Weight614.17
FormulaC33H44ClN3O6
Cas No.461023-63-2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

Aplaviroc HydrochlorideAplaviroc hydrochlorideGW 873140
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