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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that acts by enhancing Hsp expression and directly impacting protein aggregation, clearance of misfolded assemblies, and the proteasome-ubiquitin system. This compound is known for its ability to protect motor neurons. |
In vivo | Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 days) demonstrated a protective effect against cholecystokinin-octapeptide (CCK)-induced acute pancreatitis in male Wistar rats weighing 240 to 270 g. The compound was administered intragastrically at a dosage of 20 mg/kg for a duration of 5 days, resulting in a protective outcome against acute pancreatitis induced by CCK. |
Alias | Arimoclomol citrate, BRX-220 citrate |
Molecular Weight | 505.91 |
Formula | C20H28ClN3O10 |
Cas No. | 368860-21-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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