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Arimoclomol maleate

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Catalog No. T13554Cas No. 289893-26-1
Alias BRX-220

Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.

Arimoclomol maleate

Arimoclomol maleate

🥰Excellent
Purity: 99.98%
Catalog No. T13554Alias BRX-220Cas No. 289893-26-1
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.
Pack SizePriceAvailabilityQuantity
5 mg$39In Stock
10 mg$72In Stock
25 mg$147In Stock
50 mg$247In Stock
1 mL x 10 mM (in DMSO)$43In Stock
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Purity:99.98%
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Product Introduction

Bioactivity
Description
Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer.
In vivo
Arimoclomol, administered for 5 d, has a protective effect against CCK-induced acute pancreatitis. Repeated CCK treatment results in the typical laboratory and morphological changes of experimentally induced pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased in the animals treated with Arimoclomol [1]. Arimoclomol is a co-inducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease [2].
AliasBRX-220
Chemical Properties
Molecular Weight429.85
FormulaC18H24ClN3O7
Cas No.289893-26-1
SmilesOC(=O)\C=C/C(O)=O.O[C@@H](CO\N=C(/Cl)c1ccc[n+]([O-])c1)CN1CCCCC1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 250 mg/mL (581.60 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.3264 mL11.6320 mL23.2639 mL116.3196 mL
5 mM0.4653 mL2.3264 mL4.6528 mL23.2639 mL
10 mM0.2326 mL1.1632 mL2.3264 mL11.6320 mL
20 mM0.1163 mL0.5816 mL1.1632 mL5.8160 mL
50 mM0.0465 mL0.2326 mL0.4653 mL2.3264 mL
100 mM0.0233 mL0.1163 mL0.2326 mL1.1632 mL

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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