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Azido-PEG1-C2-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system [within cells].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $40 | 2-4 weeks | |
50 mg | $64 | 2-4 weeks | |
100 mg | $100 | 2-4 weeks | |
500 mg | $246 | 2-4 weeks |
Description | Azido-PEG1-C2-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules, thereby enabling selective protein degradation via the ubiquitin-proteasome system [within cells]. |
In vitro | PROTACs consist of two ligands joined by a linker: one targets an E3 ubiquitin ligase and the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 159.14 |
Formula | C5H9N3O3 |
Cas No. | 1393330-34-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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