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Azido-PEG23-amine is a PEG-based linker used in PROTACs, facilitating the joining of two essential ligands to enable selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG23-amine is a PEG-based linker used in PROTACs, facilitating the joining of two essential ligands to enable selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one targets an E3 ubiquitin ligase and the other binds to the target protein. They utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins [1]. |
Molecular Weight | 1099.3 |
Formula | C48H98N4O23 |
Cas No. | 2172677-19-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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