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BAY-678 racemate

Catalog No. T19202Cas No. 675103-35-2

BAY-678 racemate is a racemate of BAY-678, an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).

BAY-678 racemate

BAY-678 racemate

Catalog No. T19202Cas No. 675103-35-2
BAY-678 racemate is a racemate of BAY-678, an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
BAY-678 racemate is a racemate of BAY-678, an orally bioavailable, selective, and cell-permeable inhibitor of human neutrophil elastase (HNE; IC50: 20 nM).
Chemical Properties
Molecular Weight400.35
FormulaC20H15F3N4O2
Cas No.675103-35-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 150 mg/mL (374.67 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4978 mL12.4891 mL24.9781 mL124.8907 mL
5 mM0.4996 mL2.4978 mL4.9956 mL24.9781 mL
10 mM0.2498 mL1.2489 mL2.4978 mL12.4891 mL
20 mM0.1249 mL0.6245 mL1.2489 mL6.2445 mL
50 mM0.0500 mL0.2498 mL0.4996 mL2.4978 mL
100 mM0.0250 mL0.1249 mL0.2498 mL1.2489 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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