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BLM-IN-1

Catalog No. T10557Cas No. 2056014-40-3

BLM-IN-1 is a potent inhibitor of Bloom syndrome protein (BLM) with a KD of 1.81 μM and IC50 of 0.95 μM. It induces DNA damage response, apoptosis, and proliferation arrest in cancer cells.

BLM-IN-1

BLM-IN-1

Catalog No. T10557Cas No. 2056014-40-3
BLM-IN-1 is a potent inhibitor of Bloom syndrome protein (BLM) with a KD of 1.81 μM and IC50 of 0.95 μM. It induces DNA damage response, apoptosis, and proliferation arrest in cancer cells.
Pack SizePriceAvailabilityQuantity
25 mg$1,4306-8 weeks
50 mg$1,8606-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
BLM-IN-1 is a potent inhibitor of Bloom syndrome protein (BLM) with a KD of 1.81 μM and IC50 of 0.95 μM. It induces DNA damage response, apoptosis, and proliferation arrest in cancer cells.
Targets&IC50
BLM:1.95 μM
Chemical Properties
Molecular Weight462.6
FormulaC28H35FN4O
Cas No.2056014-40-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 8.33 mg/mL (18.01 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1617 mL10.8085 mL21.6169 mL108.0847 mL
5 mM0.4323 mL2.1617 mL4.3234 mL21.6169 mL
10 mM0.2162 mL1.0808 mL2.1617 mL10.8085 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

BLMIN1BLM-IN-1BLM IN 1
Related Tags: buy BLM-IN-1 | purchase BLM-IN-1 | BLM-IN-1 cost | order BLM-IN-1 | BLM-IN-1 chemical structure | BLM-IN-1 formula | BLM-IN-1 molecular weight
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