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BMS-214662

BMS-214662
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BMS-214662

Catalog No. T10567Cas No. 195987-41-8
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors and selectively targets CML stem cells/progenitors with antitumor activity.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
25 mg$2,2706-8 weeks
50 mg$2,9806-8 weeks
100 mg$4,0006-8 weeks
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Product Introduction

Bioactivity
Description
BMS-214662 is a potent and selective farnesyl transferase inhibitor that induces mitochondrial apoptosis in primitive CD34+ chronic myeloid leukemia (CML) stem cells/progenitors and selectively targets CML stem cells/progenitors with antitumor activity.
Chemical Properties
Molecular Weight489.61
FormulaC25H23N5O2S2
Cas No.195987-41-8
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (204.24 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0424 mL10.2122 mL20.4244 mL102.1221 mL
5 mM0.4085 mL2.0424 mL4.0849 mL20.4244 mL
10 mM0.2042 mL1.0212 mL2.0424 mL10.2122 mL
20 mM0.1021 mL0.5106 mL1.0212 mL5.1061 mL
50 mM0.0408 mL0.2042 mL0.4085 mL2.0424 mL
100 mM0.0204 mL0.1021 mL0.2042 mL1.0212 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
1 Enter information below:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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