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BMS-639623

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Catalog No. T30535Cas No. 675122-44-8
Alias UNII-PON9OFP69G, PON9OFP69G, CHEMBL399495, BMS 639623

BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma.

BMS-639623

BMS-639623

😃Good
Catalog No. T30535Alias UNII-PON9OFP69G, PON9OFP69G, CHEMBL399495, BMS 639623Cas No. 675122-44-8
BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma.
Pack SizePriceAvailabilityQuantity
25 mg$2,1208-10 weeks
50 mg$2,7808-10 weeks
100 mg$3,7008-10 weeks
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Product Introduction

Bioactivity
Description
BMS-639623 is a CCR3 antagonist with a picomolar inhibitory effect on eosinophilic chemotaxis and can be used in the treatment of asthma.
Targets&IC50
CCR3:0.3 nM (IC50)
AliasUNII-PON9OFP69G, PON9OFP69G, CHEMBL399495, BMS 639623
Chemical Properties
Molecular Weight481.57
FormulaC25H32FN7O2
Cas No.675122-44-8
Relative Density.1.33 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

CHEMBL 399495BMS639623CHEMBL-399495BMS-639623
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