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Biotin-PEG3-alcohol, a PEG-based linker for PROTACs, connects two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by exploiting the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Biotin-PEG3-alcohol, a PEG-based linker for PROTACs, connects two essential ligands to form PROTAC molecules. This linker facilitates selective protein degradation by exploiting the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two distinct ligands linked by a connector—one targeting an E3 ubiquitin ligase and the other the desired protein—exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins [PROTACs]. |
Alias | (+)-Biotin-PEG3-OH |
Molecular Weight | 375.48 |
Formula | C16H29N3O5S |
Cas No. | 289714-02-9 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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