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Bis-PEG4-sulfonic acid is a PEG-based linker for PROTACs, facilitating the conjugation of essential ligands critical for PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $46 | 5 days |
Description | Bis-PEG4-sulfonic acid is a PEG-based linker for PROTACs, facilitating the conjugation of essential ligands critical for PROTAC molecule formation. It enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one targets an E3 ubiquitin ligase and the other targets the protein of interest. They utilize the intracellular ubiquitin-proteasome system for the selective degradation of target proteins[1]. |
Molecular Weight | 366.41 |
Formula | C10H22O10S2 |
Cas No. | 1807539-08-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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