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CMLD010509

Name: CMLD010509
Brand: TargetMol
SKU: T10846
Price: 30 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T10846Cas No. 256497-58-2

Alias SDS-1-021

CMLD010509 (SDS-1-021) is a highly selective inhibitor of the oncogenic translation program that supports multiple myeloma (MM), targeting key oncoproteins such as MDM2, CCND1, MYC, MAF, and MCL-1.

CMLD010509

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Catalog No. T10846Alias SDS-1-021Cas No. 256497-58-2

CMLD010509 (SDS-1-021) is a highly selective inhibitor of the oncogenic translation program that supports multiple myeloma (MM), targeting key oncoproteins such as MDM2, CCND1, MYC, MAF, and MCL-1.

Pack Size	Price	Availability
25 mg	$1,520	6-8 weeks
50 mg	$1,980	6-8 weeks
100 mg	$2,500	6-8 weeks

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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	CMLD010509 (SDS-1-021) is a highly selective inhibitor of the oncogenic translation program that supports multiple myeloma (MM), targeting key oncoproteins such as MDM2, CCND1, MYC, MAF, and MCL-1.
In vitro	CMLD010509 is a potent and selective translation inhibitor through an eIF4E phosphorylation-independent mechanism. CMLD010509 shows an IC50 below 10 nM for most MM cell lines and induces apoptosis.
Alias	SDS-1-021

Chemical Properties

Molecular Weight	556.4
Formula	C₂₇H₂₆BrNO₇
Cas No.	256497-58-2
Relative Density.	1.519 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CMLD010509CMLD-010509CMLD 010509