Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,520.00 | |
50 mg | 8-10 weeks | $ 1,980.00 | |
100 mg | 8-10 weeks | $ 2,500.00 |
Description | CP-96486 is a potent and orally active antagonist of leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor (Kis: 20 and 24 nM). |
Targets&IC50 | LTD4:20 nM (ki), PAF receptor:24 nM (ki) |
In vitro | CP-96486 antagonizes 3H-LTD4 binding to guinea pig lung membranes and 3H-PAF binding to rabbit platelets (Kis: 20 and 24 nM). |
In vivo | In guinea pigs, CP-96486 inhibits iv LTD4- and iv PAF-induced bronchoconstriction (ED50s: 0.27 and 0.26 mg/kg p.o.). |
Molecular Weight | 502.99 |
Formula | C31H23ClN4O |
CAS No. | 139401-45-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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CP-96486 139401-45-9 Others CP96486 CP 96486 inhibitor inhibit