Shopping Cart

Remove All
Your shopping cart is currently empty

CWHM-1008

Name: CWHM-1008
Brand: TargetMol
SKU: T10902
Price: -1 USD
Availability: InStock
Rating: 4.5 (1 reviews)

😃Good

Catalog No. T10902Cas No. 2362539-97-5

CWHM-1008 is an effective oral antimalarial drug. The EC50 values of the drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains are 46 and 21 nM, respectively.

CWHM-1008

😃Good

Catalog No. T10902Cas No. 2362539-97-5

CWHM-1008 is an effective oral antimalarial drug. The EC50 values of the drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains are 46 and 21 nM, respectively.

Pack Size	Price	Availability
2 mg	$218	5 days
5 mg	$347	5 days
25 mg	$987	6-8 weeks
50 mg	$1,360	6-8 weeks
100 mg	$2,190	6-8 weeks

Bulk & Custom

Add to Cart

Questions

Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	CWHM-1008 is an effective oral antimalarial drug. The EC50 values of the drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains are 46 and 21 nM, respectively.
Targets&IC50	P. falciparum (3D7):46 nM (EC50), P. falciparum (Dd2):21 nM (EC50)

Chemical Properties

Molecular Weight	405.46
Formula	C₂₂H₂₆F₃N₃O
Cas No.	2362539-97-5
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 250 mg/mL (616.58 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4663 mL	12.3317 mL	24.6633 mL	123.3167 mL
5 mM	0.4933 mL	2.4663 mL	4.9327 mL	24.6633 mL
10 mM	0.2466 mL	1.2332 mL	2.4663 mL	12.3317 mL
20 mM	0.1233 mL	0.6166 mL	1.2332 mL	6.1658 mL
50 mM	0.0493 mL	0.2466 mL	0.4933 mL	2.4663 mL
100 mM	0.0247 mL	0.1233 mL	0.2466 mL	1.2332 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

CWHM1008CWHM 1008CWHM-1008