Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with IC50 value of 19 nM.
Description | CYM 9484 is a selective and potent neuropeptide Y (NPY) Y2 receptor antagonist with IC50 value of 19 nM. |
Targets&IC50 | NPYY2 receptor:19 nM |
In vitro | SF-11 is a selective brain-permeable NPY Y2 receptor antagonist with IC50 value of 190 nM. A systematic study of the SAR of the hit molecule SF-11 can identify a selective and highly effective small molecule NPY Y2 receptor antagonist CYM 9484 . CYM 9484 is ten times more effective than the hit molecule SF-11. CYM 9484 is prepared by coupling α, α-diphenylpiperidino-4-methanol with various aryl isothiocyanates. |
Molecular Weight | 509.68 |
Formula | C27H31N3O3S2 |
CAS No. | 1383478-94-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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CYM 9484 1383478-94-1 Others CYM-9484 CYM9484 inhibitor inhibit