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Cletoquine oxalate

Name: Cletoquine oxalate
Brand: TargetMol
SKU: T10835L
Price: 30 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T10835LCas No. 14142-64-4

Alias Desethylhydroxychloroquine oxalate

Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine, with antiviral efficacy against the chikungunya virus (CHIKV), antimalarial effects, and potential for treating autoimmune diseases.

Cletoquine oxalate

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Catalog No. T10835LAlias Desethylhydroxychloroquine oxalateCas No. 14142-64-4

Pack Size	Price	Availability
5 mg	564 €	1-2 weeks
25 mg	1.444 €	1-2 weeks
50 mg	1.881 €	1-2 weeks
100 mg	2.375 €	1-2 weeks

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Product Introduction

Bioactivity

Description	Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine, with antiviral efficacy against the chikungunya virus (CHIKV), antimalarial effects, and potential for treating autoimmune diseases.
In vivo	Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice to determine the concentration of Cletoquine in blood and tissues. The tissue-to-blood concentration ratio (Kp) is ≥1, indicating tissue accumulation of Cletoquine. The Cletoquine Kp ratios in descending order are liver (114.3) > kidney (24.4) > spleen (19.3) > lungs (16.5) > heart (5.5) [3].
Alias	Desethylhydroxychloroquine oxalate

Chemical Properties

Molecular Weight	397.85
Formula	C₁₈H₂₄ClN₃O₅
Cas No.	14142-64-4
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Desethylhydroxychloroquine OxalateCletoquine OxalateCletoquine oxalateChikungunya virus (CHIKV)