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Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine, with antiviral efficacy against the chikungunya virus (CHIKV), antimalarial effects, and potential for treating autoimmune diseases.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $594 | 1-2 weeks | |
25 mg | $1,520 | 1-2 weeks | |
50 mg | $1,980 | 1-2 weeks | |
100 mg | $2,500 | 1-2 weeks |
Description | Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine, with antiviral efficacy against the chikungunya virus (CHIKV), antimalarial effects, and potential for treating autoimmune diseases. |
In vivo | Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice to determine the concentration of Cletoquine in blood and tissues. The tissue-to-blood concentration ratio (Kp) is ≥1, indicating tissue accumulation of Cletoquine. The Cletoquine Kp ratios in descending order are liver (114.3) > kidney (24.4) > spleen (19.3) > lungs (16.5) > heart (5.5) [3]. |
Alias | Desethylhydroxychloroquine oxalate |
Molecular Weight | 397.85 |
Formula | C18H24ClN3O5 |
Cas No. | 14142-64-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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