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Cletoquine oxalate

Catalog No. T10835LCas No. 14142-64-4
Alias Desethylhydroxychloroquine oxalate

Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine, with antiviral efficacy against the chikungunya virus (CHIKV), antimalarial effects, and potential for treating autoimmune diseases.

Cletoquine oxalate

Cletoquine oxalate

Catalog No. T10835LAlias Desethylhydroxychloroquine oxalateCas No. 14142-64-4
Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine, with antiviral efficacy against the chikungunya virus (CHIKV), antimalarial effects, and potential for treating autoimmune diseases.
Pack SizePriceAvailabilityQuantity
5 mg$5941-2 weeks
25 mg$1,5201-2 weeks
50 mg$1,9801-2 weeks
100 mg$2,5001-2 weeks
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Product Introduction

Bioactivity
Description
Cletoquine oxalate (Desethylhydroxychloroquine oxalate) is a major active metabolite of Hydroxychloroquine, with antiviral efficacy against the chikungunya virus (CHIKV), antimalarial effects, and potential for treating autoimmune diseases.
In vivo
Hydroxychloroquine (5 mg/kg intravenously) is administered to BALB/c mice to determine the concentration of Cletoquine in blood and tissues. The tissue-to-blood concentration ratio (Kp) is ≥1, indicating tissue accumulation of Cletoquine. The Cletoquine Kp ratios in descending order are liver (114.3) > kidney (24.4) > spleen (19.3) > lungs (16.5) > heart (5.5) [3].
AliasDesethylhydroxychloroquine oxalate
Chemical Properties
Molecular Weight397.85
FormulaC18H24ClN3O5
Cas No.14142-64-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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