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Cletoquine

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Purity:97.26%

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COA HNMR HPLC

Cletoquine

Catalog No. T10835Cas No. 4298-15-1

Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.

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Pack Size	Price	Availability
1 mg	$291	In Stock
5 mg	$715	In Stock
10 mg	$987	In Stock
25 mg	$1,480	In Stock
50 mg	$1,980	In Stock
1 mL x 10 mM (in DMSO)	$688	In Stock

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Product Introduction

Bioactivity

Description	Cletoquine is a major active metabolite of Hydroxychloroquine. Cletoquine has the ability to against the chikungunya virus (CHIKV). Cletoquine has antimalarial effects and has the potential for autoimmune disease treatment.
In vivo	Hydroxychloroquine is administered intravenously at a dosage of 5 mg/kg to BALB/c mice to assess the Cletoquine levels in blood and tissues. A tissue to blood concentration ratio (Kp) of ≥1 signifies Cletoquine's accumulation in tissues. The observed descending order of the Cletoquine Kp ratios across various tissues is liver (114.3), kidney (24.4), spleen (19.3), lungs (16.5), and heart (5.5).
Alias	Desethylhydroxychloroquine

Chemical Properties

Molecular Weight	307.82
Formula	C16H22ClN3O
Cas No.	4298-15-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 55 mg/mL (178.68 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2487 mL	16.2433 mL	32.4865 mL	162.4326 mL
5 mM	0.6497 mL	3.2487 mL	6.4973 mL	32.4865 mL
10 mM	0.3249 mL	1.6243 mL	3.2487 mL	16.2433 mL
20 mM	0.1624 mL	0.8122 mL	1.6243 mL	8.1216 mL
50 mM	0.0650 mL	0.3249 mL	0.6497 mL	3.2487 mL
100 mM	0.0325 mL	0.1624 mL	0.3249 mL	1.6243 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

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