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Cyclophilin inhibitor 1

Catalog No. T10919   CAS 1509904-96-4

Cyclophilin inhibitor 1 is an effective and orally bioavailable cyclophilin A inhibitor with a Kd of 5 nM, showing potent anti-HCV activity, and an EC50 for HCV 2a of 98 nM.

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Cyclophilin inhibitor 1 Chemical Structure
Cyclophilin inhibitor 1, CAS 1509904-96-4
Pack Size Availability Price/USD Quantity
25 mg 10-14 weeks $ 3,620.00
50 mg 10-14 weeks $ 4,780.00
100 mg 10-14 weeks $ 6,700.00
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This compound is a customized synthesis product. We have a strong synthesis team with excellent synthesis technology and capabilities. However, due to various objective factors, there is a low probability that the synthesis will not be successful. If you need to learn more, please feel free to consult us, we will serve you wholeheartedly.
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Cyclophilin inhibitor 1 is an effective and orally bioavailable cyclophilin A inhibitor with a Kd of 5 nM, showing potent anti-HCV activity, and an EC50 for HCV 2a of 98 nM.
Targets&IC50 Cyclophilin A:5 nM (Kd), HCV 2a:98 nM (EC50)
In vitro Cyclophilin inhibitor 1 inhibits HCV 2a activity with an EC50 of 98 nM.
Molecular Weight 593.67
Formula C31H39N5O7
CAS No. 1509904-96-4

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

TargetMolReferences and Literature

1. Mackman RL, et al. Discovery of a Potent and Orally Bioavailable Cyclophilin Inhibitor Derived from the Sanglifehrin Macrocycle. J Med Chem. 2018 Nov 8;61(21):9473-9499.

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Keywords

Cyclophilin inhibitor 1 1509904-96-4 Others inhibitor inhibit

 

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