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DNP-PEG4-alcohol is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $46 | 5 days |
Description | DNP-PEG4-alcohol is a PEG-based linker for PROTACs, facilitating the formation of PROTAC molecules by joining two essential ligands, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets the specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 359.33 |
Formula | C14H21N3O8 |
Cas No. | 1807520-99-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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