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DSPE-PEG36-DBCO, a PEG-based linker for PROTACs, connects two essential ligands necessary for forming PROTAC molecules, thereby facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DSPE-PEG36-DBCO, a PEG-based linker for PROTACs, connects two essential ligands necessary for forming PROTAC molecules, thereby facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are comprised of two distinct ligands linked together: one binds to an E3 ubiquitin ligase, and the other targets a specific protein. They harness the cellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 2664.29 |
Formula | C133H240N3O47P |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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