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DSPE-PEG46-Folate is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | DSPE-PEG46-Folate is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, comprising two ligands joined by a linker—one targeting an E3 ubiquitin ligase and the other the desired protein—harness the ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 3240.89 |
Formula | C153H284N9O60P |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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