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Dasatinib metabolite M6

Name: Dasatinib metabolite M6
Brand: TargetMol
SKU: T37645
Rating: 4.5 (1 reviews)

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Catalog No. T37645Cas No. 910297-53-9

Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative derivative of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1].

Dasatinib metabolite M6

😃Good

Catalog No. T37645Cas No. 910297-53-9

Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative derivative of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1].

Pack Size	Price	Availability	Quantity
2 mg	$595	5 days
5 mg	$970	7-10 days

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Product Introduction

Bioactivity

Description

Dasatinib metabolite M6 (Dasatinib carboxylic acid) is an oxidative derivative of Dasatinib, a potent and orally active inhibitor of both Bcr-Abl and Src family tyrosine kinases[1].

Chemical Properties

Molecular Weight	501.99
Formula	C₂₂H₂₄ClN₇O₃S
Cas No.	910297-53-9

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (199.21 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.9921 mL	9.9604 mL	19.9207 mL	99.6036 mL
5 mM	0.3984 mL	1.9921 mL	3.9841 mL	19.9207 mL
10 mM	0.1992 mL	0.9960 mL	1.9921 mL	9.9604 mL
20 mM	0.0996 mL	0.4980 mL	0.9960 mL	4.9802 mL
50 mM	0.0398 mL	0.1992 mL	0.3984 mL	1.9921 mL
100 mM	0.0199 mL	0.0996 mL	0.1992 mL	0.9960 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Dasatinib metabolite M6Dasatinib metabolite M-6