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Diacetazotol

Catalog No. T13651Cas No. 83-63-6
Alias Diacetotoluide

Diacetazotol (Diacetotoluide) has activity against dioxin-induced ethoxyisochromamide-O-deethylase (EROD,IC50 = 75±4 nM).

Diacetazotol

Diacetazotol

Catalog No. T13651Alias DiacetotoluideCas No. 83-63-6
Diacetazotol (Diacetotoluide) has activity against dioxin-induced ethoxyisochromamide-O-deethylase (EROD,IC50 = 75±4 nM).
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Product Introduction

Bioactivity
Description
Diacetazotol (Diacetotoluide) has activity against dioxin-induced ethoxyisochromamide-O-deethylase (EROD,IC50 = 75±4 nM).
Targets&IC50
EROD:75±4 nM
In vitro
Diacetazotol can inhibit dioxin toxicity[1].
AliasDiacetotoluide
Chemical Properties
Molecular Weight309.36
FormulaC18H19N3O2
Cas No.83-63-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (258.60 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.2325 mL16.1624 mL32.3248 mL161.6240 mL
5 mM0.6465 mL3.2325 mL6.4650 mL32.3248 mL
10 mM0.3232 mL1.6162 mL3.2325 mL16.1624 mL
20 mM0.1616 mL0.8081 mL1.6162 mL8.0812 mL
50 mM0.0646 mL0.3232 mL0.6465 mL3.2325 mL
100 mM0.0323 mL0.1616 mL0.3232 mL1.6162 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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