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Emicerfont

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Catalog No. T15214Cas No. 786701-13-1
Alias GW876008

Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).

Emicerfont

Emicerfont

😃Good
Catalog No. T15214Alias GW876008Cas No. 786701-13-1
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).
Pack SizePriceAvailabilityQuantity
25 mg$1,9708-10 weeks
50 mg$2,5808-10 weeks
100 mg$3,4008-10 weeks
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Product Introduction

Bioactivity
Description
Emicerfont is an antagonist of the corticotropin-releasing factor type 1 receptor (IC50: 66 nM).
Targets&IC50
CRF1 receptor:66 nM
In vivo
Emicerfont (10 mg/kg) treatment, decreases i.c.v. CRF-induced gerbil forepaw treading and marmoset defensive postures. Emicerfont (30 mg/kg) treatment, also reduces rat pup ultrasonic vocalization.
AliasGW876008
Chemical Properties
Molecular Weight404.46
FormulaC22H24N6O2
Cas No.786701-13-1
Relative Density.1.38 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

GW-876008EmicerfontGW 876008
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