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Etifoxine

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Catalog No. T13691Cas No. 21715-46-8
Alias HOE 36-801

Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. GABAA receptor Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration. Etifoxine(HOE 36-801) is potentiator of GABAA receptor function in cultured neurons.

Etifoxine

Etifoxine

😃Good
Catalog No. T13691Alias HOE 36-801Cas No. 21715-46-8
Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. GABAA receptor Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration. Etifoxine(HOE 36-801) is potentiator of GABAA receptor function in cultured neurons.
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2 mg$355 days
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Product Introduction

Bioactivity
Description
Etifoxine preferentially acts on β2 or β3 subunit-containing GABAA receptors. GABAA receptor Etifoxine exhibits anxiolytic activity in rodents and humans with no sedative, myorelaxant or mnesic side effects. Etifoxine acts as a ligand of the translocator protein (TSPO); promotes axonal regeneration. Etifoxine(HOE 36-801) is potentiator of GABAA receptor function in cultured neurons.
AliasHOE 36-801
Chemical Properties
Molecular Weight300.78
FormulaC17H17ClN2O
Cas No.21715-46-8
Relative Density.1.2g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 100 mg/mL (332.47 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.3247 mL16.6234 mL33.2469 mL166.2345 mL
5 mM0.6649 mL3.3247 mL6.6494 mL33.2469 mL
10 mM0.3325 mL1.6623 mL3.3247 mL16.6234 mL
20 mM0.1662 mL0.8312 mL1.6623 mL8.3117 mL
50 mM0.0665 mL0.3325 mL0.6649 mL3.3247 mL
100 mM0.0332 mL0.1662 mL0.3325 mL1.6623 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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