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Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based linker derived from fluorenylmethoxycarbonyl (Fmoc) used for the efficient synthesis of PROTACs (proteolysis-targeting chimeras)[1], offering a practical solution for connecting desired molecules and targeting specific proteins for degradation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Fmoc-PEG3-CH2CH2-NHS ester is a PEG-based linker derived from fluorenylmethoxycarbonyl (Fmoc) used for the efficient synthesis of PROTACs (proteolysis-targeting chimeras)[1], offering a practical solution for connecting desired molecules and targeting specific proteins for degradation. |
In vitro | PROTACs consist of two distinct ligands linked together: one targets an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1]. |
Molecular Weight | 540.56 |
Formula | C28H32N2O9 |
Cas No. | 1352827-47-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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