Powder: -20°C for 3 years | In solvent: -80°C for 1 year
GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | Inquiry | $ 108.00 | |
2 mg | Inquiry | $ 179.00 | |
5 mg | Inquiry | $ 311.00 | |
10 mg | Inquiry | $ 486.00 | |
25 mg | Inquiry | $ 873.00 | |
50 mg | Inquiry | $ 1,454.00 | |
100 mg | Inquiry | $ 1,981.00 | |
200 mg | Inquiry | Inquiry | |
500 mg | Inquiry | Inquiry | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 334.00 |
Description | GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM). |
Targets&IC50 | GRK2:30 nM, GRK5:7.1 μM |
In vitro | GRKs-IN-1 hydrochloride (Compound 14as) is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine. |
Synonyms | GRK2-IN-1 hydrochloride |
Molecular Weight | 488.94 |
Formula | C24H26ClFN4O4 |
CAS No. | T13714L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 250 mg/mL (511.31 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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GRK2-IN-1 hydrochloride (2055990-90-2 free base) T13714L GPCR/G Protein GRK GRK2-IN-1 Hydrochloride 2055990-90-2 GRK-2-IN-1 hydrochloride (2055990-90-2 free base) GRK2IN1 hydrochloride (2055990902 free base) GRK2-IN-1 hydrochloride 2055990-90-2 free base GRK2 IN 1 hydrochloride (2055990 90 2 free base) inhibitor inhibit