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HATU

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Catalog No. T21354Cas No. 148893-10-1

HATU is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU is used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds.

HATU

HATU

🥰Excellent
Purity: 99.81%
Catalog No. T21354Cas No. 148893-10-1
HATU is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU is used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds.
Pack SizePriceAvailabilityQuantity
5 mg$29In Stock
10 mg$42In Stock
25 mg$68In Stock
50 mg$98In Stock
100 mg$147In Stock
200 mg$198In Stock
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Purity:99.81%
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Product Introduction

Bioactivity
Description
HATU is a reagent used in peptide coupling chemistry to generate an active ester from a carboxylic acid. HATU is used along with Hünig's base (N,N-diisopropylethylamine, DIPEA) to form amide bonds.
Chemical Properties
Molecular Weight380.23
FormulaC10H15F6N6OP
Cas No.148893-10-1
SmilesF[P-](F)(F)(F)(F)F.CN(C)C(On1nnc2cccnc12)=[N+](C)C
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: Insoluble
DMSO: 18.33 mg/mL (48.22 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.6300 mL13.1499 mL26.2999 mL131.4994 mL
5 mM0.5260 mL2.6300 mL5.2600 mL26.2999 mL
10 mM0.2630 mL1.3150 mL2.6300 mL13.1499 mL
20 mM0.1315 mL0.6575 mL1.3150 mL6.5750 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
%
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Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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